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A new form of rapid binocular plasticity in adult with amblyopia
Amblyopia is a neurological disorder of binocular vision affecting up to 3% of the population resulting from a disrupted period of early visual development. Recently, it has been shown that vision can be partially restored by intensive monocular or dichoptic training (4–6 weeks). This can occur even...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770967/ https://www.ncbi.nlm.nih.gov/pubmed/24026421 http://dx.doi.org/10.1038/srep02638 |
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author | Zhou, Jiawei Thompson, Benjamin Hess, Robert F. |
author_facet | Zhou, Jiawei Thompson, Benjamin Hess, Robert F. |
author_sort | Zhou, Jiawei |
collection | PubMed |
description | Amblyopia is a neurological disorder of binocular vision affecting up to 3% of the population resulting from a disrupted period of early visual development. Recently, it has been shown that vision can be partially restored by intensive monocular or dichoptic training (4–6 weeks). This can occur even in adults owing to a residual degree of brain plasticity initiated by repetitive and successive sensory stimulation. Here we show that the binocular imbalance that characterizes amblyopia can be reduced by occluding the amblyopic eye with a translucent patch for as little as 2.5 hours, suggesting a degree of rapid binocular plasticity in adults resulting from a lack of sensory stimulation. The integrated binocular benefit is larger in our amblyopic group than in our normal control group. We propose that this rapid improvement in function, as a result of reduced sensory stimulation, represents a new form of plasticity operating at a binocular site. |
format | Online Article Text |
id | pubmed-3770967 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-37709672013-09-12 A new form of rapid binocular plasticity in adult with amblyopia Zhou, Jiawei Thompson, Benjamin Hess, Robert F. Sci Rep Article Amblyopia is a neurological disorder of binocular vision affecting up to 3% of the population resulting from a disrupted period of early visual development. Recently, it has been shown that vision can be partially restored by intensive monocular or dichoptic training (4–6 weeks). This can occur even in adults owing to a residual degree of brain plasticity initiated by repetitive and successive sensory stimulation. Here we show that the binocular imbalance that characterizes amblyopia can be reduced by occluding the amblyopic eye with a translucent patch for as little as 2.5 hours, suggesting a degree of rapid binocular plasticity in adults resulting from a lack of sensory stimulation. The integrated binocular benefit is larger in our amblyopic group than in our normal control group. We propose that this rapid improvement in function, as a result of reduced sensory stimulation, represents a new form of plasticity operating at a binocular site. Nature Publishing Group 2013-09-12 /pmc/articles/PMC3770967/ /pubmed/24026421 http://dx.doi.org/10.1038/srep02638 Text en Copyright © 2013, Macmillan Publishers Limited. All rights reserved http://creativecommons.org/licenses/by-nc-sa/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-ShareALike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/ |
spellingShingle | Article Zhou, Jiawei Thompson, Benjamin Hess, Robert F. A new form of rapid binocular plasticity in adult with amblyopia |
title | A new form of rapid binocular plasticity in adult with amblyopia |
title_full | A new form of rapid binocular plasticity in adult with amblyopia |
title_fullStr | A new form of rapid binocular plasticity in adult with amblyopia |
title_full_unstemmed | A new form of rapid binocular plasticity in adult with amblyopia |
title_short | A new form of rapid binocular plasticity in adult with amblyopia |
title_sort | new form of rapid binocular plasticity in adult with amblyopia |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770967/ https://www.ncbi.nlm.nih.gov/pubmed/24026421 http://dx.doi.org/10.1038/srep02638 |
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