The ClC-3 chloride channel associated with microtubules is a target of paclitaxel in its induced-apoptosis

Recent evidences show that cationic fluxes play a pivotal role in cell apoptosis. In this study, the roles of Cl(−) channels in paclitaxel-induced apoptosis were investigated in nasopharyngeal carcinoma CNE-2Z cells. Chloride current and apoptosis were induced by paclitaxel and inhibited by chloride...

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Detalles Bibliográficos
Autores principales: Zhang, Haifeng, Li, Huarong, Yang, Lili, Deng, Zhiqin, Luo, Hai, Ye, Dong, Bai, Zhiquan, Zhu, Linyan, Ye, Wencai, Wang, Liwei, Chen, Lixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770968/
https://www.ncbi.nlm.nih.gov/pubmed/24026363
http://dx.doi.org/10.1038/srep02615

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