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Identifying Core Herbal Treatments for Children with Asthma: Implication from a Chinese Herbal Medicine Database in Taiwan

Asthma is one of the most common allergic respiratory diseases around the world and places great burden on medical payment. Chinese herbal medicine (CHM) is commonly used for Taiwanese children to control diseases. The aim of this study is to analyze the CHM prescriptions for asthmatic children by u...

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Autores principales: Chen, Hsing-Yu, Lin, Yi-Hsuan, Thien, Peck-Foong, Chang, Shih-Chieh, Chen, Yu-Chun, Lo, Su-Shun, Yang, Sien-Hung, Chen, Jiun-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771466/
https://www.ncbi.nlm.nih.gov/pubmed/24066007
http://dx.doi.org/10.1155/2013/125943
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author Chen, Hsing-Yu
Lin, Yi-Hsuan
Thien, Peck-Foong
Chang, Shih-Chieh
Chen, Yu-Chun
Lo, Su-Shun
Yang, Sien-Hung
Chen, Jiun-Liang
author_facet Chen, Hsing-Yu
Lin, Yi-Hsuan
Thien, Peck-Foong
Chang, Shih-Chieh
Chen, Yu-Chun
Lo, Su-Shun
Yang, Sien-Hung
Chen, Jiun-Liang
author_sort Chen, Hsing-Yu
collection PubMed
description Asthma is one of the most common allergic respiratory diseases around the world and places great burden on medical payment. Chinese herbal medicine (CHM) is commonly used for Taiwanese children to control diseases. The aim of this study is to analyze the CHM prescriptions for asthmatic children by using a nationwide clinical database. The National Health Insurance Research Database (NHIRD) was used to perform this study. Medical records from 1997 to 2009 with diagnosis with asthma made for children aged 6 to 18 were included into the analysis. Association rule mining and social network analysis were used to analyze the prevalence of single CHM and its combinations. Ma-Xing-Gan-Shi-Tang (MXGST) was the most commonly used herbal formula (HF) (20.2% of all prescriptions), followed by Xiao-Qing-Long-Tang (13.1%) and Xing-Su-San (12.8%). Zhe Bei Mu is the most frequently used single herb (SH) (14.6%), followed by Xing Ren (10.7%). MXGST was commonly used with Zhe Bei Mu (3.5%) and other single herbs capable of dispelling phlegm. Besides, MXGST was the core formula to relieve asthma. Further studies about efficacy and drug safety are needed for the CHM commonly used for asthma based on the result of this study.
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spelling pubmed-37714662013-09-24 Identifying Core Herbal Treatments for Children with Asthma: Implication from a Chinese Herbal Medicine Database in Taiwan Chen, Hsing-Yu Lin, Yi-Hsuan Thien, Peck-Foong Chang, Shih-Chieh Chen, Yu-Chun Lo, Su-Shun Yang, Sien-Hung Chen, Jiun-Liang Evid Based Complement Alternat Med Research Article Asthma is one of the most common allergic respiratory diseases around the world and places great burden on medical payment. Chinese herbal medicine (CHM) is commonly used for Taiwanese children to control diseases. The aim of this study is to analyze the CHM prescriptions for asthmatic children by using a nationwide clinical database. The National Health Insurance Research Database (NHIRD) was used to perform this study. Medical records from 1997 to 2009 with diagnosis with asthma made for children aged 6 to 18 were included into the analysis. Association rule mining and social network analysis were used to analyze the prevalence of single CHM and its combinations. Ma-Xing-Gan-Shi-Tang (MXGST) was the most commonly used herbal formula (HF) (20.2% of all prescriptions), followed by Xiao-Qing-Long-Tang (13.1%) and Xing-Su-San (12.8%). Zhe Bei Mu is the most frequently used single herb (SH) (14.6%), followed by Xing Ren (10.7%). MXGST was commonly used with Zhe Bei Mu (3.5%) and other single herbs capable of dispelling phlegm. Besides, MXGST was the core formula to relieve asthma. Further studies about efficacy and drug safety are needed for the CHM commonly used for asthma based on the result of this study. Hindawi Publishing Corporation 2013 2013-08-28 /pmc/articles/PMC3771466/ /pubmed/24066007 http://dx.doi.org/10.1155/2013/125943 Text en Copyright © 2013 Hsing-Yu Chen et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Chen, Hsing-Yu
Lin, Yi-Hsuan
Thien, Peck-Foong
Chang, Shih-Chieh
Chen, Yu-Chun
Lo, Su-Shun
Yang, Sien-Hung
Chen, Jiun-Liang
Identifying Core Herbal Treatments for Children with Asthma: Implication from a Chinese Herbal Medicine Database in Taiwan
title Identifying Core Herbal Treatments for Children with Asthma: Implication from a Chinese Herbal Medicine Database in Taiwan
title_full Identifying Core Herbal Treatments for Children with Asthma: Implication from a Chinese Herbal Medicine Database in Taiwan
title_fullStr Identifying Core Herbal Treatments for Children with Asthma: Implication from a Chinese Herbal Medicine Database in Taiwan
title_full_unstemmed Identifying Core Herbal Treatments for Children with Asthma: Implication from a Chinese Herbal Medicine Database in Taiwan
title_short Identifying Core Herbal Treatments for Children with Asthma: Implication from a Chinese Herbal Medicine Database in Taiwan
title_sort identifying core herbal treatments for children with asthma: implication from a chinese herbal medicine database in taiwan
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771466/
https://www.ncbi.nlm.nih.gov/pubmed/24066007
http://dx.doi.org/10.1155/2013/125943
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