Grape-Derived Polyphenols Prevent Doxorubicin-Induced Blunted EDH-Mediated Relaxations in the Rat Mesenteric Artery: Role of ROS and Angiotensin II

This study determined whether doxorubicin, an anticancer agent, impairs endothelium-dependent relaxations mediated by nitric oxide (NO) and endothelium-derived hyperpolarization (EDH) in the mesenteric artery and, if so, the mechanism underlying the protective effect of red wine polyphenols (RWPs),...

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Detalles Bibliográficos
Autores principales: Idris-Khodja, Noureddine, Di Marco, Paola, Farhat, Mona, Geny, Bernard, Schini-Kerth, Valérie B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771472/
https://www.ncbi.nlm.nih.gov/pubmed/24066014
http://dx.doi.org/10.1155/2013/516017

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