Hologram quantitative structure–activity relationship and comparative molecular field analysis studies within a series of tricyclic phthalimide HIV-1 integrase inhibitors

Acquired immunodeficiency syndrome is a public health problem worldwide caused by the Human immunodeficiency virus (HIV). Treatment with antiretroviral drugs is the best option for viral suppression, reducing morbidity and mortality. However, viral resistance in HIV-1 therapy has been reported. HIV-...

Descripción completa

Detalles Bibliográficos
Autores principales: de Oliveira Magalhães, Uiaran, de Souza, Alessandra Mendonça Teles, Albuquerque, Magaly Girão, de Brito, Monique Araújo, Bello, Murilo Lamim, Cabral, Lucio Mendes, Rodrigues, Carlos Rangel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771852/
https://www.ncbi.nlm.nih.gov/pubmed/24039405
http://dx.doi.org/10.2147/DDDT.S47057

Ejemplares similares

Ejemplares similares