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Visualizing SNVs to quantify allele-specific expression in single cells

We present a high efficiency fluorescence in situ hybridization method for detecting single nucleotide variants (SNVs) on individual RNA transcripts, both exonic and intronic. We used this method to quantify allelic expression at the population and single cell level, and also to distinguish maternal...

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Detalles Bibliográficos
Autores principales:	Levesque, Marshall J., Ginart, Paul, Wei, Yichen, Raj, Arjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771873/ https://www.ncbi.nlm.nih.gov/pubmed/23913259 http://dx.doi.org/10.1038/nmeth.2589

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