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Acute Neonatal Infections ‘Lock-In’ a Suboptimal CD8+ T Cell Repertoire with Impaired Recall Responses
Microbial infection during various stages of human development produces widely different clinical outcomes, yet the links between age-related changes in the immune compartment and functional immunity remain unclear. The ability of the immune system to respond to specific antigens and mediate protect...
Autores principales: | Rudd, Brian D., Venturi, Vanessa, Smith, Norah L., Nzingha, Kito, Goldberg, Emily L., Li, Gang, Nikolich-Zugich, Janko, Davenport, Miles P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771883/ https://www.ncbi.nlm.nih.gov/pubmed/24068921 http://dx.doi.org/10.1371/journal.ppat.1003572 |
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