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Bacterial Clearance Is Improved in Septic Mice by Platelet-Activating Factor-Acetylhydrolase (PAF-AH) Administration
Current evidence indicates that dysregulation of the host inflammatory response to infectious agents is central to the mortality of patients with sepsis. Strategies to block inflammatory mediators such as PAF have been investigated as adjuvant therapies for sepsis. PAF-AH, the enzyme responsible for...
Autores principales: | Teixeira-da-Cunha, Mariana G. A., Gomes, Rachel N., Roehrs, Nathassia, Bozza, Fernando A., Prescott, Stephen M., Stafforini, Diana, Zimmerman, Guy A., Bozza, Patricia T., Castro-Faria-Neto, Hugo C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771912/ https://www.ncbi.nlm.nih.gov/pubmed/24069320 http://dx.doi.org/10.1371/journal.pone.0074567 |
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