Cargando…

Two tyrosine-based sorting signals in the Cx43 C-terminus cooperate to mediate gap junction endocytosis

Gap junction (GJ) channels that electrically and chemically couple neighboring cells are formed when two hemichannels (connexons) of apposed cells dock head-on in the extracellular space. Remarkably, docked connexons are inseparable under physiological conditions, and we and others have shown that G...

Descripción completa

Detalles Bibliográficos
Autores principales: Fong, John T., Kells, Rachael M., Falk, Matthias M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771946/
https://www.ncbi.nlm.nih.gov/pubmed/23885125
http://dx.doi.org/10.1091/mbc.E13-02-0111