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Two tyrosine-based sorting signals in the Cx43 C-terminus cooperate to mediate gap junction endocytosis
Gap junction (GJ) channels that electrically and chemically couple neighboring cells are formed when two hemichannels (connexons) of apposed cells dock head-on in the extracellular space. Remarkably, docked connexons are inseparable under physiological conditions, and we and others have shown that G...
Autores principales: | Fong, John T., Kells, Rachael M., Falk, Matthias M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771946/ https://www.ncbi.nlm.nih.gov/pubmed/23885125 http://dx.doi.org/10.1091/mbc.E13-02-0111 |
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