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Catabolism of Exogenous Lactate Reveals It as a Legitimate Metabolic Substrate in Breast Cancer
Lactate accumulation in tumors has been associated with metastases and poor overall survival in cancer patients. Lactate promotes angiogenesis and metastasis, providing rationale for understanding how it is processed by cells. The concentration of lactate in tumors is a balance between the amount pr...
Autores principales: | Kennedy, Kelly M., Scarbrough, Peter M., Ribeiro, Anthony, Richardson, Rachel, Yuan, Hong, Sonveaux, Pierre, Landon, Chelsea D., Chi, Jen-Tsan, Pizzo, Salvatore, Schroeder, Thies, Dewhirst, Mark W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771963/ https://www.ncbi.nlm.nih.gov/pubmed/24069390 http://dx.doi.org/10.1371/journal.pone.0075154 |
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