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Catabolism of Exogenous Lactate Reveals It as a Legitimate Metabolic Substrate in Breast Cancer

Lactate accumulation in tumors has been associated with metastases and poor overall survival in cancer patients. Lactate promotes angiogenesis and metastasis, providing rationale for understanding how it is processed by cells. The concentration of lactate in tumors is a balance between the amount pr...

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Detalles Bibliográficos
Autores principales: Kennedy, Kelly M., Scarbrough, Peter M., Ribeiro, Anthony, Richardson, Rachel, Yuan, Hong, Sonveaux, Pierre, Landon, Chelsea D., Chi, Jen-Tsan, Pizzo, Salvatore, Schroeder, Thies, Dewhirst, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771963/
https://www.ncbi.nlm.nih.gov/pubmed/24069390
http://dx.doi.org/10.1371/journal.pone.0075154

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