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Fenretinide Corrects the Imbalance between Omega-6 to Omega-3 Polyunsaturated Fatty Acids and Inhibits Macrophage Inflammatory Mediators via the ERK Pathway
We previously identified Fragile X-related protein 1 (FXR1) as an RNA-binding protein involved in the post-transcriptional control of TNF and other cytokines in macrophages. Macrophages derived from FXR1-KO mice overexpress several inflammatory cytokines including TNF. Recently, we showed that fenre...
Autores principales: | Lachance, Claude, Wojewodka, Gabriella, Skinner, Tom A. A., Guilbault, Claudine, De Sanctis, Juan B., Radzioch, Danuta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771966/ https://www.ncbi.nlm.nih.gov/pubmed/24069363 http://dx.doi.org/10.1371/journal.pone.0074875 |
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