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Engraftment of Mouse Embryonic Stem Cells Differentiated by Default Leads to Neuroprotection, Behaviour Revival and Astrogliosis in Parkinsonian Rats

We report here protection against rotenone-induced behavioural dysfunction, striatal dopamine depletion and nigral neuronal loss, following intra-striatal transplantation of neurons differentiated from murine embryonic stem cells (mES). mES maintained in serum free medium exhibited increase in neuro...

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Detalles Bibliográficos
Autores principales: Tripathy, Debasmita, Haobam, Reena, Nair, Ranju, Mohanakumar, Kochupurackal P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772067/
https://www.ncbi.nlm.nih.gov/pubmed/24069147
http://dx.doi.org/10.1371/journal.pone.0072501