A Neutralizing Monoclonal Antibody Targeting the Acid-Sensitive Region in Chikungunya Virus E2 Protects from Disease

The mosquito-borne alphavirus, chikungunya virus (CHIKV), has recently reemerged, producing the largest epidemic ever recorded for this virus, with up to 6.5 million cases of acute and chronic rheumatic disease. There are currently no licensed vaccines for CHIKV and current anti-inflammatory drug tr...

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Detalles Bibliográficos
Autores principales: Selvarajah, Suganya, Sexton, Nicole R., Kahle, Kristen M., Fong, Rachel H., Mattia, Kimberly-Anne, Gardner, Joy, Lu, Kai, Liss, Nathan M., Salvador, Beatriz, Tucker, David F., Barnes, Trevor, Mabila, Manu, Zhou, Xiangdong, Rossini, Giada, Rucker, Joseph B., Sanders, David Avram, Suhrbier, Andreas, Sambri, Vittorio, Michault, Alain, Muench, Marcus O., Doranz, Benjamin J., Simmons, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772074/
https://www.ncbi.nlm.nih.gov/pubmed/24069479
http://dx.doi.org/10.1371/journal.pntd.0002423

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