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A Link between ORC-Origin Binding Mechanisms and Origin Activation Time Revealed in Budding Yeast
Eukaryotic DNA replication origins are selected in G1-phase when the origin recognition complex (ORC) binds chromosomal positions and triggers molecular events culminating in the initiation of DNA replication (a.k.a. origin firing) during S-phase. Each chromosome uses multiple origins for its duplic...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772097/ https://www.ncbi.nlm.nih.gov/pubmed/24068963 http://dx.doi.org/10.1371/journal.pgen.1003798 |