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Transcriptional regulation by STAT1 and STAT2 in the interferon JAK-STAT pathway
STAT1 and STAT2 proteins are key mediators of type I and type III interferon (IFN) signaling, and are essential components of the cellular antiviral response and adaptive immunity. They associate with IFN regulatory factor 9 (IRF9) to form a heterotrimeric transcription factor complex known as ISGF3...
Autores principales: | Au-Yeung, Nancy, Mandhana, Roli, Horvath, Curt M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772101/ https://www.ncbi.nlm.nih.gov/pubmed/24069549 http://dx.doi.org/10.4161/jkst.23931 |
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