Cargando…

Computational models of the JAK1/2-STAT1 signaling

Despite a conceptually simple mechanism of signaling, the JAK-STAT pathway exhibits considerable behavioral complexity. Computational pathway models are tools to investigate in detail signaling process. They integrate well with experimental studies, helping to explain molecular dynamics and to state...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gambin, Anna, Charzyńska, Agata, Ellert-Miklaszewska, Aleksandra, Rybiński, Mikołaj
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772111/ https://www.ncbi.nlm.nih.gov/pubmed/24069559 http://dx.doi.org/10.4161/jkst.24672

Ejemplares similares

Computational modeling of sphingolipid metabolism
por: Wronowska, Weronika, et al.
Publicado: (2015)

Modelling the efficacy of hyperthermia treatment
por: Rybiński, Mikołaj, et al.
Publicado: (2013)

The signal transducers Stat1 and Stat3 and their novel target Jmjd3 drive the expression of inflammatory genes in microglia
por: Przanowski, Piotr, et al.
Publicado: (2013)

Transcriptional regulation by STAT1 and STAT2 in the interferon JAK-STAT pathway
por: Au-Yeung, Nancy, et al.
Publicado: (2013)

JAK/STAT signaling in hepatocellular carcinoma
por: Hin Tang, Justin Jit, et al.
Publicado: (2020)

Narrative-based computational modelling of the Gp130/JAK/STAT signalling pathway
por: Guerriero, Maria Luisa, et al.
Publicado: (2009)

Delivery of the VIVIT Peptide to Human Glioma Cells to Interfere with Calcineurin-NFAT Signaling
por: Ellert-Miklaszewska, Aleksandra, et al.
Publicado: (2021)

Tav4SB: integrating tools for analysis of kinetic models of biological systems
por: Rybiński, Mikołaj, et al.
Publicado: (2012)

Cannabinoid signalling in glioma cells
por: Kaminska, Bozena, et al.
Publicado: (2015)

Post-Receptor Inhibitors of the GHR-JAK2-STAT Pathway in the Growth Hormone Signal Transduction
por: Wójcik, Maciej, et al.
Publicado: (2018)

Integrin Signaling in Glioma Pathogenesis: From Biology to Therapy
por: Ellert-Miklaszewska, Aleksandra, et al.
Publicado: (2020)

JAK-STAT signaling and myocardial glucose metabolism
por: Frias, Miguel A, et al.
Publicado: (2013)

The role of JAK-STAT signaling within the CNS
por: Nicolas, Celine S., et al.
Publicado: (2013)

The JAK inhibitor tofacitinib suppresses synovial JAK1-STAT signalling in rheumatoid arthritis
por: Boyle, D L, et al.
Publicado: (2015)

JAK-STAT and feeding
por: Ladyman, Sharon R., et al.
Publicado: (2013)

A review of JAK–STAT signalling in the pathogenesis of spondyloarthritis and the role of JAK inhibition
por: McInnes, Iain B, et al.
Publicado: (2021)

Targeting the tumor microenvironment: JAK-STAT3 signaling
por: Bournazou, Eirini, et al.
Publicado: (2013)

JAK-STAT signaling in cardiomyogenesis of cardiac stem cells
por: Mohri, Tomomi, et al.
Publicado: (2012)

Leptin-Induced JAK/STAT Signaling and Cancer Growth
por: Mullen, McKay, et al.
Publicado: (2016)

The Role and Therapeutic Targeting of JAK/STAT Signaling in Glioblastoma
por: Ou, Alexander, et al.
Publicado: (2021)

Effects of JAK2-STAT3 signaling after cerebral insults
por: Raible, Daniel J, et al.
Publicado: (2014)

Dynamic Regulation of JAK-STAT Signaling Through the Prolactin Receptor Predicted by Computational Modeling
por: Mortlock, Ryland D., et al.
Publicado: (2020)

Is the JAK-STAT Signaling Pathway Involved in the Pathogenesis of Depression?
por: Gałecka, Małgorzata, et al.
Publicado: (2022)

The Interaction of the IFNγ/JAK/STAT1 and JAK/STAT3 Signalling Pathways in EGFR-Mutated Lung Adenocarcinoma Cells
por: Han, Yaguang, et al.
Publicado: (2022)

Myeloproliferative neoplasms and the JAK/STAT signaling pathway: an overview
por: de Freitas, Renata Mendes, et al.
Publicado: (2015)

The JAK/STAT signaling pathway: from bench to clinic
por: Hu, Xiaoyi, et al.
Publicado: (2021)

JAK-STAT Signalling Pathway in Cancer
por: Brooks, Andrew J., et al.
Publicado: (2020)

Negative Regulators of JAK/STAT Signaling in Rheumatoid Arthritis and Osteoarthritis
por: Malemud, Charles J.
Publicado: (2017)

JAK-STAT and bone metabolism
por: Li, Jiliang
Publicado: (2013)

Evolution of the JAK-STAT pathway
por: Liongue, Clifford, et al.
Publicado: (2013)

JAK-STAT signaling in stem cells and their niches in Drosophila
por: Bausek, Nina
Publicado: (2013)

JAK/STAT Signalling in Huntington’s Disease Immune Cells
por: Träger, Ulrike, et al.
Publicado: (2013)

Mechanisms of chronic JAK-STAT3-SOCS3 signaling in obesity
por: Wunderlich, Claudia M., et al.
Publicado: (2013)

Ubiquitin-mediated regulation of JAK-STAT signaling in embryonic stem cells
por: Hatakeyama, Shigetsugu
Publicado: (2012)

The JAK-STAT pathway in hypertrophic stress signaling and genomic stress response
por: Wagner, Michael A., et al.
Publicado: (2012)

Drosophila Jak/STAT Signaling: Regulation and Relevance in Human Cancer and Metastasis
por: Trivedi, Sunny, et al.
Publicado: (2018)

JAK/STAT Signaling and Cervical Cancer: From the Cell Surface to the Nucleus
por: Valle-Mendiola, Arturo, et al.
Publicado: (2023)

The Role of LNK (SH2B3) in the Regulation of JAK-STAT Signalling in Haematopoiesis
por: Morris, Rhiannon, et al.
Publicado: (2021)

JAK/STAT signaling and human in vitro myogenesis
por: Trenerry, Marissa K, et al.
Publicado: (2011)

JAK/STAT signaling in diabetic kidney disease
por: Liu, Yingjun, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_953it1ec8j8sssmte3sdt292ad