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The cardioprotective effects of urocortin are mediated via activation of the Src tyrosine kinase-STAT3 pathway
Src tyrosine kinase family was recently identified as a novel upstream modulator of MAP kinase subfamily, p42/p44, whose activation is required for urocortin (Ucn)-mediated cardioprotection. Src kinase was also shown to reduce apoptosis in different cancer cell lines, enhancing phosphorylation and D...
Autores principales: | Chen-Scarabelli, Carol, Saravolatz II, Louis, Mccaukey, Roy, Scarabelli, Gabriele, Di Rezze, Justin, Mohanty, Bibhu, Barry, Sean, Latchman, David, Georgiadis, Vassilis, McCormick, James, Saravolatz, Louis, Knight, Richard, Faggian, Giuseppe, Narula, Jagat, Stephanou, Anastasis, Scarabelli, Tiziano M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772114/ https://www.ncbi.nlm.nih.gov/pubmed/24069562 http://dx.doi.org/10.4161/jkst.24812 |
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