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Galactose 6-O-Sulfotransferases Are Not Required for the Generation of Siglec-F Ligands in Leukocytes or Lung Tissue

Eosinophil accumulation is a characteristic feature of the immune response to parasitic worms and allergens. The cell surface carbohydrate-binding receptor Siglec-F is highly expressed on eosinophils and negatively regulates their accumulation during inflammation. Although endogenous ligands for Sig...

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Detalles Bibliográficos
Autores principales: Patnode, Michael L., Cheng, Chu-Wen, Chou, Chi-Chi, Singer, Mark S., Elin, Matilda S., Uchimura, Kenji, Crocker, Paul R., Khoo, Kay-Hooi, Rosen, Steven D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772201/
https://www.ncbi.nlm.nih.gov/pubmed/23880769
http://dx.doi.org/10.1074/jbc.M113.485409