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1-[(6-Chloropyridin-3-yl)methyl]-10-nitro-1,2,3,5,6,7,8,9-octahydro-5,9-methanoimidazo[1,2-a]azocin-5-ol
In the title compound, C(16)H(19)ClN(4)O(3), the cyclohexane ring displays a chair formation and the tetrahydropyridine ring displays an envelope conformation with the methylene C atom as the flap; the imidazolidine ring also displays an envelope conformation with a methylene C atom as the flap...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772455/ https://www.ncbi.nlm.nih.gov/pubmed/24046598 http://dx.doi.org/10.1107/S1600536813014402 |
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author | Cui, Shu-Xia Zhang, Guang-You Tian, Zhong-Zhen |
author_facet | Cui, Shu-Xia Zhang, Guang-You Tian, Zhong-Zhen |
author_sort | Cui, Shu-Xia |
collection | PubMed |
description | In the title compound, C(16)H(19)ClN(4)O(3), the cyclohexane ring displays a chair formation and the tetrahydropyridine ring displays an envelope conformation with the methylene C atom as the flap; the imidazolidine ring also displays an envelope conformation with a methylene C atom as the flap. In the crystal, O—H⋯N hydrogen bonds between hydroxy groups and pyridine rings link inversion-related molecules into dimers. Weak C—H⋯O hydrogen bonds further link the dimers into supramolecular chains running along the c axis. |
format | Online Article Text |
id | pubmed-3772455 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-37724552013-09-17 1-[(6-Chloropyridin-3-yl)methyl]-10-nitro-1,2,3,5,6,7,8,9-octahydro-5,9-methanoimidazo[1,2-a]azocin-5-ol Cui, Shu-Xia Zhang, Guang-You Tian, Zhong-Zhen Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(16)H(19)ClN(4)O(3), the cyclohexane ring displays a chair formation and the tetrahydropyridine ring displays an envelope conformation with the methylene C atom as the flap; the imidazolidine ring also displays an envelope conformation with a methylene C atom as the flap. In the crystal, O—H⋯N hydrogen bonds between hydroxy groups and pyridine rings link inversion-related molecules into dimers. Weak C—H⋯O hydrogen bonds further link the dimers into supramolecular chains running along the c axis. International Union of Crystallography 2013-06-08 /pmc/articles/PMC3772455/ /pubmed/24046598 http://dx.doi.org/10.1107/S1600536813014402 Text en © Cui et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Cui, Shu-Xia Zhang, Guang-You Tian, Zhong-Zhen 1-[(6-Chloropyridin-3-yl)methyl]-10-nitro-1,2,3,5,6,7,8,9-octahydro-5,9-methanoimidazo[1,2-a]azocin-5-ol |
title | 1-[(6-Chloropyridin-3-yl)methyl]-10-nitro-1,2,3,5,6,7,8,9-octahydro-5,9-methanoimidazo[1,2-a]azocin-5-ol |
title_full | 1-[(6-Chloropyridin-3-yl)methyl]-10-nitro-1,2,3,5,6,7,8,9-octahydro-5,9-methanoimidazo[1,2-a]azocin-5-ol |
title_fullStr | 1-[(6-Chloropyridin-3-yl)methyl]-10-nitro-1,2,3,5,6,7,8,9-octahydro-5,9-methanoimidazo[1,2-a]azocin-5-ol |
title_full_unstemmed | 1-[(6-Chloropyridin-3-yl)methyl]-10-nitro-1,2,3,5,6,7,8,9-octahydro-5,9-methanoimidazo[1,2-a]azocin-5-ol |
title_short | 1-[(6-Chloropyridin-3-yl)methyl]-10-nitro-1,2,3,5,6,7,8,9-octahydro-5,9-methanoimidazo[1,2-a]azocin-5-ol |
title_sort | 1-[(6-chloropyridin-3-yl)methyl]-10-nitro-1,2,3,5,6,7,8,9-octahydro-5,9-methanoimidazo[1,2-a]azocin-5-ol |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772455/ https://www.ncbi.nlm.nih.gov/pubmed/24046598 http://dx.doi.org/10.1107/S1600536813014402 |
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