6-(4-Meth­oxy­phen­yl)-6a-nitro-6,6a,6b,7,8,9,10,12a-octa­hydro­spiro­[chromeno[3,4-a]indolizine-12,3′-indolin]-2′-one

In the title compound, C(29)H(27)N(3)O(5), the hydropyran ring adopts an envelope conformation with the methine C atom bearing the para-meth­oxy­benzene ring as the flap. The central pyrrolidine ring has a twist conformation on the N—C bond involving the spiro C atom. The piperidine ring adopts a ch...

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Autores principales: Devi, Seenivasan Karthiga, Srinivasan, Thothadri, Rao, Jonnalagadda Naga Siva, Raghunathan, Raghavachary, Velmurugan, Devadasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772479/
https://www.ncbi.nlm.nih.gov/pubmed/24046622
http://dx.doi.org/10.1107/S1600536813015341
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author Devi, Seenivasan Karthiga
Srinivasan, Thothadri
Rao, Jonnalagadda Naga Siva
Raghunathan, Raghavachary
Velmurugan, Devadasan
author_facet Devi, Seenivasan Karthiga
Srinivasan, Thothadri
Rao, Jonnalagadda Naga Siva
Raghunathan, Raghavachary
Velmurugan, Devadasan
author_sort Devi, Seenivasan Karthiga
collection PubMed
description In the title compound, C(29)H(27)N(3)O(5), the hydropyran ring adopts an envelope conformation with the methine C atom bearing the para-meth­oxy­benzene ring as the flap. The central pyrrolidine ring has a twist conformation on the N—C bond involving the spiro C atom. The piperidine ring adopts a chair conformation. An intra­molecular C—H⋯O contact closes an S(7) ring. In the crystal, inversion dimers linked by C—H⋯O inter­actions generate R (2) (2)(18) loops and N—H⋯O hydrogen bonds connect the dimers into [100] chains.
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spelling pubmed-37724792013-09-17 6-(4-Meth­oxy­phen­yl)-6a-nitro-6,6a,6b,7,8,9,10,12a-octa­hydro­spiro­[chromeno[3,4-a]indolizine-12,3′-indolin]-2′-one Devi, Seenivasan Karthiga Srinivasan, Thothadri Rao, Jonnalagadda Naga Siva Raghunathan, Raghavachary Velmurugan, Devadasan Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(29)H(27)N(3)O(5), the hydropyran ring adopts an envelope conformation with the methine C atom bearing the para-meth­oxy­benzene ring as the flap. The central pyrrolidine ring has a twist conformation on the N—C bond involving the spiro C atom. The piperidine ring adopts a chair conformation. An intra­molecular C—H⋯O contact closes an S(7) ring. In the crystal, inversion dimers linked by C—H⋯O inter­actions generate R (2) (2)(18) loops and N—H⋯O hydrogen bonds connect the dimers into [100] chains. International Union of Crystallography 2013-06-08 /pmc/articles/PMC3772479/ /pubmed/24046622 http://dx.doi.org/10.1107/S1600536813015341 Text en © Devi et al. 2013 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Devi, Seenivasan Karthiga
Srinivasan, Thothadri
Rao, Jonnalagadda Naga Siva
Raghunathan, Raghavachary
Velmurugan, Devadasan
6-(4-Meth­oxy­phen­yl)-6a-nitro-6,6a,6b,7,8,9,10,12a-octa­hydro­spiro­[chromeno[3,4-a]indolizine-12,3′-indolin]-2′-one
title 6-(4-Meth­oxy­phen­yl)-6a-nitro-6,6a,6b,7,8,9,10,12a-octa­hydro­spiro­[chromeno[3,4-a]indolizine-12,3′-indolin]-2′-one
title_full 6-(4-Meth­oxy­phen­yl)-6a-nitro-6,6a,6b,7,8,9,10,12a-octa­hydro­spiro­[chromeno[3,4-a]indolizine-12,3′-indolin]-2′-one
title_fullStr 6-(4-Meth­oxy­phen­yl)-6a-nitro-6,6a,6b,7,8,9,10,12a-octa­hydro­spiro­[chromeno[3,4-a]indolizine-12,3′-indolin]-2′-one
title_full_unstemmed 6-(4-Meth­oxy­phen­yl)-6a-nitro-6,6a,6b,7,8,9,10,12a-octa­hydro­spiro­[chromeno[3,4-a]indolizine-12,3′-indolin]-2′-one
title_short 6-(4-Meth­oxy­phen­yl)-6a-nitro-6,6a,6b,7,8,9,10,12a-octa­hydro­spiro­[chromeno[3,4-a]indolizine-12,3′-indolin]-2′-one
title_sort 6-(4-meth­oxy­phen­yl)-6a-nitro-6,6a,6b,7,8,9,10,12a-octa­hydro­spiro­[chromeno[3,4-a]indolizine-12,3′-indolin]-2′-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772479/
https://www.ncbi.nlm.nih.gov/pubmed/24046622
http://dx.doi.org/10.1107/S1600536813015341
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