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Ophthalmic viscoelastic device injection for the treatment of flat anterior chamber after trabeculectomy: a case series study

PURPOSE: Flat anterior chamber (FAC) in association with overfiltration is a complication after trabeculectomy. The aim of the current study was to investigate the efficacy of injection of an ophthalmic viscoelastic device (OVD) to treat FAC after trabeculectomy in a retrospective consecutive case s...

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Autores principales: Hosoda, Shingo, Yuki, Kenya, Ono, Takeshi, Tsubota, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772763/
https://www.ncbi.nlm.nih.gov/pubmed/24043927
http://dx.doi.org/10.2147/OPTH.S51165
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author Hosoda, Shingo
Yuki, Kenya
Ono, Takeshi
Tsubota, Kazuo
author_facet Hosoda, Shingo
Yuki, Kenya
Ono, Takeshi
Tsubota, Kazuo
author_sort Hosoda, Shingo
collection PubMed
description PURPOSE: Flat anterior chamber (FAC) in association with overfiltration is a complication after trabeculectomy. The aim of the current study was to investigate the efficacy of injection of an ophthalmic viscoelastic device (OVD) to treat FAC after trabeculectomy in a retrospective consecutive case series study. MATERIALS AND METHODS: Twenty-five consecutive patients who underwent injection of OVD for the treatment of FAC after trabeculectomy were analyzed. The primary outcome variable was the qualified success of trabeculectomy, which was defined at three different levels by the achievement of one of three IOP-related criteria with or without glaucoma medication. Kaplan–Meier plots were generated to estimate survival functions for trabeculectomy with OVD injection. RESULTS: Twenty-one patients (21/25 = 84.0%) recovered from FAC by one OVD injection. The postoperative intraocular pressure (IOP) measured at 12 months, 24 months, 36 months, 48 months, and 60 months was 14.7 ± 3.6 mmHg, 15.6 ± 7.0 mmHg, 14.2 ± 2.8 mmHg, 14.2 ± 3.8 mmHg, and 14.6 ± 2.7 mmHg, respectively. All postoperative IOP measurements were significantly lower than the preoperative IOP (P < 0.001). The probabilities of qualified success for 5 years after trabeculectomy with OVD injection were as follows: 24.4% (IOP ≦ 21 mmHg and ≧20% reduction of preoperative IOP), 16.5% (IOP ≦ 16 mmHg and ≧20% reduction) and 6.3% (IOP ≦ 12 mmHg and ≧30% reduction). One patient, who had undergone deep lamellar keratoplasty, experienced a complication associated with the injection of the viscoelastic material, Descemet’s membrane detachment. CONCLUSION: Injection of OVD may be effective for the treatment of FAC; however, the long-term success rate was relatively low.
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spelling pubmed-37727632013-09-16 Ophthalmic viscoelastic device injection for the treatment of flat anterior chamber after trabeculectomy: a case series study Hosoda, Shingo Yuki, Kenya Ono, Takeshi Tsubota, Kazuo Clin Ophthalmol Case Series PURPOSE: Flat anterior chamber (FAC) in association with overfiltration is a complication after trabeculectomy. The aim of the current study was to investigate the efficacy of injection of an ophthalmic viscoelastic device (OVD) to treat FAC after trabeculectomy in a retrospective consecutive case series study. MATERIALS AND METHODS: Twenty-five consecutive patients who underwent injection of OVD for the treatment of FAC after trabeculectomy were analyzed. The primary outcome variable was the qualified success of trabeculectomy, which was defined at three different levels by the achievement of one of three IOP-related criteria with or without glaucoma medication. Kaplan–Meier plots were generated to estimate survival functions for trabeculectomy with OVD injection. RESULTS: Twenty-one patients (21/25 = 84.0%) recovered from FAC by one OVD injection. The postoperative intraocular pressure (IOP) measured at 12 months, 24 months, 36 months, 48 months, and 60 months was 14.7 ± 3.6 mmHg, 15.6 ± 7.0 mmHg, 14.2 ± 2.8 mmHg, 14.2 ± 3.8 mmHg, and 14.6 ± 2.7 mmHg, respectively. All postoperative IOP measurements were significantly lower than the preoperative IOP (P < 0.001). The probabilities of qualified success for 5 years after trabeculectomy with OVD injection were as follows: 24.4% (IOP ≦ 21 mmHg and ≧20% reduction of preoperative IOP), 16.5% (IOP ≦ 16 mmHg and ≧20% reduction) and 6.3% (IOP ≦ 12 mmHg and ≧30% reduction). One patient, who had undergone deep lamellar keratoplasty, experienced a complication associated with the injection of the viscoelastic material, Descemet’s membrane detachment. CONCLUSION: Injection of OVD may be effective for the treatment of FAC; however, the long-term success rate was relatively low. Dove Medical Press 2013 2013-09-06 /pmc/articles/PMC3772763/ /pubmed/24043927 http://dx.doi.org/10.2147/OPTH.S51165 Text en © 2013 Hosoda et al. This work is published by Dove Medical Press Ltd, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Ltd, provided the work is properly attributed.
spellingShingle Case Series
Hosoda, Shingo
Yuki, Kenya
Ono, Takeshi
Tsubota, Kazuo
Ophthalmic viscoelastic device injection for the treatment of flat anterior chamber after trabeculectomy: a case series study
title Ophthalmic viscoelastic device injection for the treatment of flat anterior chamber after trabeculectomy: a case series study
title_full Ophthalmic viscoelastic device injection for the treatment of flat anterior chamber after trabeculectomy: a case series study
title_fullStr Ophthalmic viscoelastic device injection for the treatment of flat anterior chamber after trabeculectomy: a case series study
title_full_unstemmed Ophthalmic viscoelastic device injection for the treatment of flat anterior chamber after trabeculectomy: a case series study
title_short Ophthalmic viscoelastic device injection for the treatment of flat anterior chamber after trabeculectomy: a case series study
title_sort ophthalmic viscoelastic device injection for the treatment of flat anterior chamber after trabeculectomy: a case series study
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772763/
https://www.ncbi.nlm.nih.gov/pubmed/24043927
http://dx.doi.org/10.2147/OPTH.S51165
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