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Ca(2+) Influx and Tyrosine Kinases Trigger Bordetella Adenylate Cyclase Toxin (ACT) Endocytosis. Cell Physiology and Expression of the CD11b/CD18 Integrin Major Determinants of the Entry Route

Humans infected with Bordetella pertussis, the whooping cough bacterium, show evidences of impaired host defenses. This pathogenic bacterium produces a unique adenylate cyclase toxin (ACT) which enters human phagocytes and catalyzes the unregulated formation of cAMP, hampering important bactericidal...

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Detalles Bibliográficos
Autores principales:	Uribe, Kepa B., Martín, César, Etxebarria, Aitor, González-Bullón, David, Gómez-Bilbao, Geraxane, Ostolaza, Helena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772820/ https://www.ncbi.nlm.nih.gov/pubmed/24058533 http://dx.doi.org/10.1371/journal.pone.0074248

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