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Development of Novel (123)I-Labeled Pyridyl Benzofuran Derivatives for SPECT Imaging of β-Amyloid Plaques in Alzheimer’s Disease
Imaging of β-amyloid (Aβ) plaques in the brain may facilitate the diagnosis of cerebral β-amyloidosis, risk prediction of Alzheimer’s disease (AD), and effectiveness of anti-amyloid therapies. The purpose of this study was to evaluate novel (123)I-labeled pyridyl benzofuran derivatives as SPECT prob...
Autores principales: | Ono, Masahiro, Cheng, Yan, Kimura, Hiroyuki, Watanabe, Hiroyuki, Matsumura, Kenji, Yoshimura, Masashi, Iikuni, Shimpei, Okamoto, Yoko, Ihara, Masafumi, Takahashi, Ryosuke, Saji, Hideo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772825/ https://www.ncbi.nlm.nih.gov/pubmed/24058519 http://dx.doi.org/10.1371/journal.pone.0074104 |
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