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Characterizing Immunoglobulin Repertoire from Whole Blood by a Personal Genome Sequencer
In human immune system, V(D)J recombination produces an enormously large repertoire of immunoglobulins (Ig) so that they can tackle different antigens from bacteria, viruses and tumor cells. Several studies have demonstrated the utility of next-generation sequencers such as Roche 454 and Illumina Ge...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772839/ https://www.ncbi.nlm.nih.gov/pubmed/24058670 http://dx.doi.org/10.1371/journal.pone.0075294 |