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Epsilon PKC Increases Brain Mitochondrial SIRT1 Protein Levels via Heat Shock Protein 90 following Ischemic Preconditioning in Rats
Ischemic preconditioning is a neuroprotective mechanism whereby a sublethal ischemic exposure is protective against a subsequent lethal ischemic attack. We previously demonstrated that SIRT1, a nuclear localized stress-activated deacetylase, is vital for ischemic preconditioning neuroprotection. How...
Autores principales: | Thompson, John W., Dave, Kunjan R., Saul, Isabel, Narayanan, Srinivasan V., Perez-Pinzon, Miguel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772907/ https://www.ncbi.nlm.nih.gov/pubmed/24058702 http://dx.doi.org/10.1371/journal.pone.0075753 |
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