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Fusion Protein Vaccines Targeting Two Tumor Antigens Generate Synergistic Anti-Tumor Effects

INTRODUCTION: Human papillomavirus (HPV) has been consistently implicated in causing several kinds of malignancies, and two HPV oncogenes, E6 and E7, represent two potential target antigens for cancer vaccines. We developed two fusion protein vaccines, PE(ΔIII)/E6 and PE(ΔIII)/E7 by targeting these...

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Detalles Bibliográficos
Autores principales: Cheng, Wen-Fang, Chang, Ming-Cheng, Sun, Wei-Zen, Jen, Yu-Wei, Liao, Chao-Wei, Chen, Yun-Yuan, Chen, Chi-An
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772923/
https://www.ncbi.nlm.nih.gov/pubmed/24058440
http://dx.doi.org/10.1371/journal.pone.0071216