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Relationship between Differential Hepatic microRNA Expression and Decreased Hepatic Cytochrome P450 3A Activity in Cirrhosis

BACKGROUND AND AIM: Liver cirrhosis is associated with decreased hepatic cytochrome P4503A (CYP3A) activity but the pathogenesis of this phenomenon is not well elucidated. In this study, we examined if certain microRNAs (miRNA) are associated with decreased hepatic CYP3A activity in cirrhosis. METHO...

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Detalles Bibliográficos
Autores principales:	Vuppalanchi, Raj, Liang, Tiebing, Goswami, Chirayu Pankaj, Nalamasu, Rohit, Li, Lang, Jones, David, Wei, Rongrong, Liu, Wanqing, Sarasani, Vishal, Janga, Sarath Chandra, Chalasani, Naga
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772944/ https://www.ncbi.nlm.nih.gov/pubmed/24058572 http://dx.doi.org/10.1371/journal.pone.0074471

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