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Myeloperoxidase modulates human platelet aggregation via actin cytoskeleton reorganization and store-operated calcium entry

Myeloperoxidase (MPO) is a heme-containing enzyme released from activated leukocytes into the extracellular space during inflammation. Its main function is the production of hypohalous acids that are potent oxidants. MPO can also modulate cell signaling and inflammatory responses independently of it...

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Detalles Bibliográficos
Autores principales: Gorudko, Irina V., Sokolov, Alexey V., Shamova, Ekaterina V., Grudinina, Natalia A., Drozd, Elizaveta S., Shishlo, Ludmila M., Grigorieva, Daria V., Bushuk, Sergey B., Bushuk, Boris A., Chizhik, Sergey A., Cherenkevich, Sergey N., Vasilyev, Vadim B., Panasenko, Oleg M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773338/
https://www.ncbi.nlm.nih.gov/pubmed/24143278
http://dx.doi.org/10.1242/bio.20135314