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Myeloperoxidase modulates human platelet aggregation via actin cytoskeleton reorganization and store-operated calcium entry
Myeloperoxidase (MPO) is a heme-containing enzyme released from activated leukocytes into the extracellular space during inflammation. Its main function is the production of hypohalous acids that are potent oxidants. MPO can also modulate cell signaling and inflammatory responses independently of it...
Autores principales: | Gorudko, Irina V., Sokolov, Alexey V., Shamova, Ekaterina V., Grudinina, Natalia A., Drozd, Elizaveta S., Shishlo, Ludmila M., Grigorieva, Daria V., Bushuk, Sergey B., Bushuk, Boris A., Chizhik, Sergey A., Cherenkevich, Sergey N., Vasilyev, Vadim B., Panasenko, Oleg M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773338/ https://www.ncbi.nlm.nih.gov/pubmed/24143278 http://dx.doi.org/10.1242/bio.20135314 |
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