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Camel Milk as a Potential Therapy as an Antioxidant in Autism Spectrum Disorder (ASD)

Extensive studies have demonstrated that oxidative stress plays a vital role in the pathology of several neurological diseases, including autism spectrum disorder (ASD); those studies proposed that GSH and antioxidant enzymes have a pathophysiological role in autism. Furthermore, camel milk has emer...

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Detalles Bibliográficos
Autores principales: AL-Ayadhi, Laila Y., Elamin, Nadra Elyass
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773435/
https://www.ncbi.nlm.nih.gov/pubmed/24069051
http://dx.doi.org/10.1155/2013/602834
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author AL-Ayadhi, Laila Y.
Elamin, Nadra Elyass
author_facet AL-Ayadhi, Laila Y.
Elamin, Nadra Elyass
author_sort AL-Ayadhi, Laila Y.
collection PubMed
description Extensive studies have demonstrated that oxidative stress plays a vital role in the pathology of several neurological diseases, including autism spectrum disorder (ASD); those studies proposed that GSH and antioxidant enzymes have a pathophysiological role in autism. Furthermore, camel milk has emerged to have potential therapeutic effects in autism. The aim of the current study was to evaluate the effect of camel milk consumption on oxidative stress biomarkers in autistic children, by measuring the plasma levels of glutathione, superoxide dismutase, and myeloperoxidase before and 2 weeks after camel milk consumption, using the ELISA technique. All measured parameters exhibited significant increase after camel milk consumption (P < 0.5). These findings suggest that camel milk could play an important role in decreasing oxidative stress by alteration of antioxidant enzymes and nonenzymatic antioxidant molecules levels, as well as the improvement of autistic behaviour as demonstrated by the improved Childhood Autism Rating Scale (CARS).
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spelling pubmed-37734352013-09-25 Camel Milk as a Potential Therapy as an Antioxidant in Autism Spectrum Disorder (ASD) AL-Ayadhi, Laila Y. Elamin, Nadra Elyass Evid Based Complement Alternat Med Research Article Extensive studies have demonstrated that oxidative stress plays a vital role in the pathology of several neurological diseases, including autism spectrum disorder (ASD); those studies proposed that GSH and antioxidant enzymes have a pathophysiological role in autism. Furthermore, camel milk has emerged to have potential therapeutic effects in autism. The aim of the current study was to evaluate the effect of camel milk consumption on oxidative stress biomarkers in autistic children, by measuring the plasma levels of glutathione, superoxide dismutase, and myeloperoxidase before and 2 weeks after camel milk consumption, using the ELISA technique. All measured parameters exhibited significant increase after camel milk consumption (P < 0.5). These findings suggest that camel milk could play an important role in decreasing oxidative stress by alteration of antioxidant enzymes and nonenzymatic antioxidant molecules levels, as well as the improvement of autistic behaviour as demonstrated by the improved Childhood Autism Rating Scale (CARS). Hindawi Publishing Corporation 2013 2013-08-29 /pmc/articles/PMC3773435/ /pubmed/24069051 http://dx.doi.org/10.1155/2013/602834 Text en Copyright © 2013 L. Y. AL-Ayadhi and N. E. Elamin. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
AL-Ayadhi, Laila Y.
Elamin, Nadra Elyass
Camel Milk as a Potential Therapy as an Antioxidant in Autism Spectrum Disorder (ASD)
title Camel Milk as a Potential Therapy as an Antioxidant in Autism Spectrum Disorder (ASD)
title_full Camel Milk as a Potential Therapy as an Antioxidant in Autism Spectrum Disorder (ASD)
title_fullStr Camel Milk as a Potential Therapy as an Antioxidant in Autism Spectrum Disorder (ASD)
title_full_unstemmed Camel Milk as a Potential Therapy as an Antioxidant in Autism Spectrum Disorder (ASD)
title_short Camel Milk as a Potential Therapy as an Antioxidant in Autism Spectrum Disorder (ASD)
title_sort camel milk as a potential therapy as an antioxidant in autism spectrum disorder (asd)
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773435/
https://www.ncbi.nlm.nih.gov/pubmed/24069051
http://dx.doi.org/10.1155/2013/602834
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