The gating charge pathway of an epilepsy-associated potassium channel accommodates chemical ligands

Voltage-gated potassium (Kv) channels derive their voltage sensitivity from movement of gating charges in voltage-sensor domains (VSDs). The gating charges translocate through a physical pathway in the VSD to open or close the channel. Previous studies showed that the gating charge pathways of Shake...

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Detalles Bibliográficos
Autores principales: Li, Ping, Chen, Zhuxi, Xu, Haiyan, Sun, Haifeng, Li, Hao, Liu, Hong, Yang, Huaiyu, Gao, Zhaobing, Jiang, Hualiang, Li, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773576/
https://www.ncbi.nlm.nih.gov/pubmed/23797855
http://dx.doi.org/10.1038/cr.2013.82

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