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Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site
Merkel cell carcinoma (MCC) is an extremely rare primary neuroendocrine neoplasm of the skin that shows aggressive behavior and a poor prognosis. We report a case of a 67-year-old male with a Merkel cell carcinoma which initially presented itself as a large retroperitoneal mass. Pathological and imm...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773894/ https://www.ncbi.nlm.nih.gov/pubmed/24073348 http://dx.doi.org/10.1155/2013/131695 |
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author | Rossini, Daniele Caponnetto, Salvatore Lapadula, Vittoria De Filippis, Lucilla Del Bene, Gabriella Emiliani, Alessandra Longo, Flavia |
author_facet | Rossini, Daniele Caponnetto, Salvatore Lapadula, Vittoria De Filippis, Lucilla Del Bene, Gabriella Emiliani, Alessandra Longo, Flavia |
author_sort | Rossini, Daniele |
collection | PubMed |
description | Merkel cell carcinoma (MCC) is an extremely rare primary neuroendocrine neoplasm of the skin that shows aggressive behavior and a poor prognosis. We report a case of a 67-year-old male with a Merkel cell carcinoma which initially presented itself as a large retroperitoneal mass. Pathological and immunohistochemical analysis revealed tissue consistent with neuroendocrine carcinoma. Despite complete medical workup, no other primary MCC could be detected. While being an atypical presentation, the tumor mass showed an excellent response to the combination of chemotherapy followed by radiotherapy. |
format | Online Article Text |
id | pubmed-3773894 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-37738942013-09-26 Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site Rossini, Daniele Caponnetto, Salvatore Lapadula, Vittoria De Filippis, Lucilla Del Bene, Gabriella Emiliani, Alessandra Longo, Flavia Case Rep Oncol Med Case Report Merkel cell carcinoma (MCC) is an extremely rare primary neuroendocrine neoplasm of the skin that shows aggressive behavior and a poor prognosis. We report a case of a 67-year-old male with a Merkel cell carcinoma which initially presented itself as a large retroperitoneal mass. Pathological and immunohistochemical analysis revealed tissue consistent with neuroendocrine carcinoma. Despite complete medical workup, no other primary MCC could be detected. While being an atypical presentation, the tumor mass showed an excellent response to the combination of chemotherapy followed by radiotherapy. Hindawi Publishing Corporation 2013 2013-09-01 /pmc/articles/PMC3773894/ /pubmed/24073348 http://dx.doi.org/10.1155/2013/131695 Text en Copyright © 2013 Daniele Rossini et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Rossini, Daniele Caponnetto, Salvatore Lapadula, Vittoria De Filippis, Lucilla Del Bene, Gabriella Emiliani, Alessandra Longo, Flavia Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site |
title | Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site |
title_full | Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site |
title_fullStr | Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site |
title_full_unstemmed | Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site |
title_short | Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site |
title_sort | merkel cell carcinoma of the retroperitoneum with no identifiable primary site |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773894/ https://www.ncbi.nlm.nih.gov/pubmed/24073348 http://dx.doi.org/10.1155/2013/131695 |
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