Cargando…

Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site

Merkel cell carcinoma (MCC) is an extremely rare primary neuroendocrine neoplasm of the skin that shows aggressive behavior and a poor prognosis. We report a case of a 67-year-old male with a Merkel cell carcinoma which initially presented itself as a large retroperitoneal mass. Pathological and imm...

Descripción completa

Detalles Bibliográficos
Autores principales: Rossini, Daniele, Caponnetto, Salvatore, Lapadula, Vittoria, De Filippis, Lucilla, Del Bene, Gabriella, Emiliani, Alessandra, Longo, Flavia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773894/
https://www.ncbi.nlm.nih.gov/pubmed/24073348
http://dx.doi.org/10.1155/2013/131695
_version_ 1782284443883405312
author Rossini, Daniele
Caponnetto, Salvatore
Lapadula, Vittoria
De Filippis, Lucilla
Del Bene, Gabriella
Emiliani, Alessandra
Longo, Flavia
author_facet Rossini, Daniele
Caponnetto, Salvatore
Lapadula, Vittoria
De Filippis, Lucilla
Del Bene, Gabriella
Emiliani, Alessandra
Longo, Flavia
author_sort Rossini, Daniele
collection PubMed
description Merkel cell carcinoma (MCC) is an extremely rare primary neuroendocrine neoplasm of the skin that shows aggressive behavior and a poor prognosis. We report a case of a 67-year-old male with a Merkel cell carcinoma which initially presented itself as a large retroperitoneal mass. Pathological and immunohistochemical analysis revealed tissue consistent with neuroendocrine carcinoma. Despite complete medical workup, no other primary MCC could be detected. While being an atypical presentation, the tumor mass showed an excellent response to the combination of chemotherapy followed by radiotherapy.
format Online
Article
Text
id pubmed-3773894
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-37738942013-09-26 Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site Rossini, Daniele Caponnetto, Salvatore Lapadula, Vittoria De Filippis, Lucilla Del Bene, Gabriella Emiliani, Alessandra Longo, Flavia Case Rep Oncol Med Case Report Merkel cell carcinoma (MCC) is an extremely rare primary neuroendocrine neoplasm of the skin that shows aggressive behavior and a poor prognosis. We report a case of a 67-year-old male with a Merkel cell carcinoma which initially presented itself as a large retroperitoneal mass. Pathological and immunohistochemical analysis revealed tissue consistent with neuroendocrine carcinoma. Despite complete medical workup, no other primary MCC could be detected. While being an atypical presentation, the tumor mass showed an excellent response to the combination of chemotherapy followed by radiotherapy. Hindawi Publishing Corporation 2013 2013-09-01 /pmc/articles/PMC3773894/ /pubmed/24073348 http://dx.doi.org/10.1155/2013/131695 Text en Copyright © 2013 Daniele Rossini et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Rossini, Daniele
Caponnetto, Salvatore
Lapadula, Vittoria
De Filippis, Lucilla
Del Bene, Gabriella
Emiliani, Alessandra
Longo, Flavia
Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site
title Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site
title_full Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site
title_fullStr Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site
title_full_unstemmed Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site
title_short Merkel Cell Carcinoma of the Retroperitoneum with No Identifiable Primary Site
title_sort merkel cell carcinoma of the retroperitoneum with no identifiable primary site
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773894/
https://www.ncbi.nlm.nih.gov/pubmed/24073348
http://dx.doi.org/10.1155/2013/131695
work_keys_str_mv AT rossinidaniele merkelcellcarcinomaoftheretroperitoneumwithnoidentifiableprimarysite
AT caponnettosalvatore merkelcellcarcinomaoftheretroperitoneumwithnoidentifiableprimarysite
AT lapadulavittoria merkelcellcarcinomaoftheretroperitoneumwithnoidentifiableprimarysite
AT defilippislucilla merkelcellcarcinomaoftheretroperitoneumwithnoidentifiableprimarysite
AT delbenegabriella merkelcellcarcinomaoftheretroperitoneumwithnoidentifiableprimarysite
AT emilianialessandra merkelcellcarcinomaoftheretroperitoneumwithnoidentifiableprimarysite
AT longoflavia merkelcellcarcinomaoftheretroperitoneumwithnoidentifiableprimarysite