An Eco-Friendly Improved Protocol for the Synthesis of Bis(3-indolyl)methanes Using Poly(4-vinylpyridinium)hydrogen Sulfate as Efficient, Heterogeneous, and Recyclable Solid Acid Catalyst

Highly efficient and eco-friendly protocol for the synthesis of bis(3-indolyl)methanes by the electrophilic substitution reaction of indole with aldehydes catalyzed by poly(4-vinylpyridinium)hydrogen sulfate was described. Excellent yields, shorter reaction times, simple work-up procedure, avoiding...

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Detalles Bibliográficos
Autores principales: Banothu, Janardhan, Gali, Rajitha, Velpula, Ravibabu, Bavantula, Rajitha, Crooks, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774024/
https://www.ncbi.nlm.nih.gov/pubmed/24052864
http://dx.doi.org/10.1155/2013/616932
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author Banothu, Janardhan
Gali, Rajitha
Velpula, Ravibabu
Bavantula, Rajitha
Crooks, Peter A.
author_facet Banothu, Janardhan
Gali, Rajitha
Velpula, Ravibabu
Bavantula, Rajitha
Crooks, Peter A.
author_sort Banothu, Janardhan
collection PubMed
description Highly efficient and eco-friendly protocol for the synthesis of bis(3-indolyl)methanes by the electrophilic substitution reaction of indole with aldehydes catalyzed by poly(4-vinylpyridinium)hydrogen sulfate was described. Excellent yields, shorter reaction times, simple work-up procedure, avoiding hazardous organic solvents, and reusability of the catalyst are the most obvious advantages of this method.
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spelling pubmed-37740242013-09-19 An Eco-Friendly Improved Protocol for the Synthesis of Bis(3-indolyl)methanes Using Poly(4-vinylpyridinium)hydrogen Sulfate as Efficient, Heterogeneous, and Recyclable Solid Acid Catalyst Banothu, Janardhan Gali, Rajitha Velpula, Ravibabu Bavantula, Rajitha Crooks, Peter A. ISRN Org Chem Research Article Highly efficient and eco-friendly protocol for the synthesis of bis(3-indolyl)methanes by the electrophilic substitution reaction of indole with aldehydes catalyzed by poly(4-vinylpyridinium)hydrogen sulfate was described. Excellent yields, shorter reaction times, simple work-up procedure, avoiding hazardous organic solvents, and reusability of the catalyst are the most obvious advantages of this method. Hindawi Publishing Corporation 2013-09-02 /pmc/articles/PMC3774024/ /pubmed/24052864 http://dx.doi.org/10.1155/2013/616932 Text en Copyright © 2013 Janardhan Banothu et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Banothu, Janardhan
Gali, Rajitha
Velpula, Ravibabu
Bavantula, Rajitha
Crooks, Peter A.
An Eco-Friendly Improved Protocol for the Synthesis of Bis(3-indolyl)methanes Using Poly(4-vinylpyridinium)hydrogen Sulfate as Efficient, Heterogeneous, and Recyclable Solid Acid Catalyst
title An Eco-Friendly Improved Protocol for the Synthesis of Bis(3-indolyl)methanes Using Poly(4-vinylpyridinium)hydrogen Sulfate as Efficient, Heterogeneous, and Recyclable Solid Acid Catalyst
title_full An Eco-Friendly Improved Protocol for the Synthesis of Bis(3-indolyl)methanes Using Poly(4-vinylpyridinium)hydrogen Sulfate as Efficient, Heterogeneous, and Recyclable Solid Acid Catalyst
title_fullStr An Eco-Friendly Improved Protocol for the Synthesis of Bis(3-indolyl)methanes Using Poly(4-vinylpyridinium)hydrogen Sulfate as Efficient, Heterogeneous, and Recyclable Solid Acid Catalyst
title_full_unstemmed An Eco-Friendly Improved Protocol for the Synthesis of Bis(3-indolyl)methanes Using Poly(4-vinylpyridinium)hydrogen Sulfate as Efficient, Heterogeneous, and Recyclable Solid Acid Catalyst
title_short An Eco-Friendly Improved Protocol for the Synthesis of Bis(3-indolyl)methanes Using Poly(4-vinylpyridinium)hydrogen Sulfate as Efficient, Heterogeneous, and Recyclable Solid Acid Catalyst
title_sort eco-friendly improved protocol for the synthesis of bis(3-indolyl)methanes using poly(4-vinylpyridinium)hydrogen sulfate as efficient, heterogeneous, and recyclable solid acid catalyst
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774024/
https://www.ncbi.nlm.nih.gov/pubmed/24052864
http://dx.doi.org/10.1155/2013/616932
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