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Potentiation of Antibiofilm Activity of Amphotericin B by Superoxide Dismutase Inhibition

This study demonstrates a role for superoxide dismutases (Sods) in governing tolerance of Candida albicans biofilms to amphotericin B (AmB). Coincubation of C. albicans biofilms with AmB and the Sod inhibitors N,N′-diethyldithiocarbamate (DDC) or ammonium tetrathiomolybdate (ATM) resulted in reduced...

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Detalles Bibliográficos
Autores principales: De Brucker, Katrijn, Bink, Anna, Meert, Els, Cammue, Bruno P. A., Thevissen, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774027/
https://www.ncbi.nlm.nih.gov/pubmed/24078861
http://dx.doi.org/10.1155/2013/704654