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The Effect of Silver Nitrate Pleurodesis after a Failed Thoracoscopic Talc Poudrage

Background. Chemical pleurodesis is the procedure of choice in the management of recurrent malignant pleural effusions (MPE). Talc is probably the most effective sclerosant, with a success rate of 80%. The aim of this study is to demonstrate the effectiveness of silver nitrate solution (SNS) pleurod...

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Autores principales: Menna, Cecilia, Andreetti, Claudio, Ibrahim, Mohsen, Maurizi, Giulio, Poggi, Camilla, Barile, Rocco, Cassiano, Francesco, Rendina, Erino A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774036/
https://www.ncbi.nlm.nih.gov/pubmed/24073398
http://dx.doi.org/10.1155/2013/295890
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author Menna, Cecilia
Andreetti, Claudio
Ibrahim, Mohsen
Maurizi, Giulio
Poggi, Camilla
Barile, Rocco
Cassiano, Francesco
Rendina, Erino A.
author_facet Menna, Cecilia
Andreetti, Claudio
Ibrahim, Mohsen
Maurizi, Giulio
Poggi, Camilla
Barile, Rocco
Cassiano, Francesco
Rendina, Erino A.
author_sort Menna, Cecilia
collection PubMed
description Background. Chemical pleurodesis is the procedure of choice in the management of recurrent malignant pleural effusions (MPE). Talc is probably the most effective sclerosant, with a success rate of 80%. The aim of this study is to demonstrate the effectiveness of silver nitrate solution (SNS) pleurodesis after an unsuccessful thoracoscopic talc poudrage. Methods. Between 2011 and 2013 one hundred and nine patients with unilateral MPE underwent thoracoscopic talc poudrage. Seventeen patients who did not obtain a successful pleurodesis via thoracoscopic procedure were considered for an SNS slurry. The pleural injectate consisted of 100 mL 1% SNS with 10 mL of lidocaine (100 mg/5 mL). The SNS procedure was undertaken once and repeated with the same dose in 5 patients. Results. The duration of follow-up period was 30 days. Subjective pain was low and the same before and after SNS procedure (P value = NS). The mean daily fluid drainage was statistically different (P = 0.001) comparing values before (597.0 ± 122.8 mL) and after SNS procedure (109.1 ± 22.3 mL). After 30 days from SNS procedure recurrence of pleural effusion was observed in 2 patients (11%). Conclusions. The present study demonstrates that SNS is an effective agent for producing pleurodesis after a failed thoracoscopic talc poudrage.
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spelling pubmed-37740362013-09-26 The Effect of Silver Nitrate Pleurodesis after a Failed Thoracoscopic Talc Poudrage Menna, Cecilia Andreetti, Claudio Ibrahim, Mohsen Maurizi, Giulio Poggi, Camilla Barile, Rocco Cassiano, Francesco Rendina, Erino A. Biomed Res Int Clinical Study Background. Chemical pleurodesis is the procedure of choice in the management of recurrent malignant pleural effusions (MPE). Talc is probably the most effective sclerosant, with a success rate of 80%. The aim of this study is to demonstrate the effectiveness of silver nitrate solution (SNS) pleurodesis after an unsuccessful thoracoscopic talc poudrage. Methods. Between 2011 and 2013 one hundred and nine patients with unilateral MPE underwent thoracoscopic talc poudrage. Seventeen patients who did not obtain a successful pleurodesis via thoracoscopic procedure were considered for an SNS slurry. The pleural injectate consisted of 100 mL 1% SNS with 10 mL of lidocaine (100 mg/5 mL). The SNS procedure was undertaken once and repeated with the same dose in 5 patients. Results. The duration of follow-up period was 30 days. Subjective pain was low and the same before and after SNS procedure (P value = NS). The mean daily fluid drainage was statistically different (P = 0.001) comparing values before (597.0 ± 122.8 mL) and after SNS procedure (109.1 ± 22.3 mL). After 30 days from SNS procedure recurrence of pleural effusion was observed in 2 patients (11%). Conclusions. The present study demonstrates that SNS is an effective agent for producing pleurodesis after a failed thoracoscopic talc poudrage. Hindawi Publishing Corporation 2013 2013-09-01 /pmc/articles/PMC3774036/ /pubmed/24073398 http://dx.doi.org/10.1155/2013/295890 Text en Copyright © 2013 Cecilia Menna et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Menna, Cecilia
Andreetti, Claudio
Ibrahim, Mohsen
Maurizi, Giulio
Poggi, Camilla
Barile, Rocco
Cassiano, Francesco
Rendina, Erino A.
The Effect of Silver Nitrate Pleurodesis after a Failed Thoracoscopic Talc Poudrage
title The Effect of Silver Nitrate Pleurodesis after a Failed Thoracoscopic Talc Poudrage
title_full The Effect of Silver Nitrate Pleurodesis after a Failed Thoracoscopic Talc Poudrage
title_fullStr The Effect of Silver Nitrate Pleurodesis after a Failed Thoracoscopic Talc Poudrage
title_full_unstemmed The Effect of Silver Nitrate Pleurodesis after a Failed Thoracoscopic Talc Poudrage
title_short The Effect of Silver Nitrate Pleurodesis after a Failed Thoracoscopic Talc Poudrage
title_sort effect of silver nitrate pleurodesis after a failed thoracoscopic talc poudrage
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774036/
https://www.ncbi.nlm.nih.gov/pubmed/24073398
http://dx.doi.org/10.1155/2013/295890
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