Role of Telomere Dysfunction in Cardiac Failure in Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy (DMD), the most common inherited muscular dystrophy of childhood, leads to death due to cardiorespiratory failure. Paradoxically, mdx mice with the same genetic deficiency of dystrophin, exhibit minimal cardiac dysfunction, impeding the development of therapies. We postul...

Descripción completa

Detalles Bibliográficos
Autores principales: Mourkioti, Foteini, Kustan, Jackie, Kraft, Peggy, Day, John W., Zhao, Ming-Ming, Kost-Alimova, Maria, Protopopov, Alexei, DePinho, Ronald A., Bernstein, Daniel, Meeker, Alan K., Blau, Helen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774175/
https://www.ncbi.nlm.nih.gov/pubmed/23831727
http://dx.doi.org/10.1038/ncb2790

Ejemplares similares

Ejemplares similares