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Engineering a Replication-Competent, Propagation-Defective Middle East Respiratory Syndrome Coronavirus as a Vaccine Candidate
Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging coronavirus infecting humans that is associated with acute pneumonia, occasional renal failure, and a high mortality rate and is considered a threat to public health. The construction of a full-length infectious cDNA clone of the...
Autores principales: | Almazán, Fernando, DeDiego, Marta L., Sola, Isabel, Zuñiga, Sonia, Nieto-Torres, Jose L., Marquez-Jurado, Silvia, Andrés, German, Enjuanes, Luis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774192/ https://www.ncbi.nlm.nih.gov/pubmed/24023385 http://dx.doi.org/10.1128/mBio.00650-13 |
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