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Novel Role for the Streptococcus pneumoniae Toxin Pneumolysin in the Assembly of Biofilms

Streptococcus pneumoniae is an important commensal and pathogen responsible for almost a million deaths annually in children under five. The formation of biofilms by S. pneumoniae is important in nasopharyngeal colonization, pneumonia, and otitis media. Pneumolysin (Ply) is a toxin that contributes...

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Detalles Bibliográficos
Autores principales: Shak, Joshua R., Ludewick, Herbert P., Howery, Kristen E., Sakai, Fuminori, Yi, Hong, Harvey, Richard M., Paton, James C., Klugman, Keith P., Vidal, Jorge E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774193/
https://www.ncbi.nlm.nih.gov/pubmed/24023386
http://dx.doi.org/10.1128/mBio.00655-13