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Differential Role of PTEN Phosphatase in Chemotactic Growth Cone Guidance
Negatively targeting the tumor suppressor and phosphoinositide phosphatase PTEN (phosphatase and tensin homologue) promotes axon regrowth after injury. How PTEN functions in axon guidance has remained unknown. Here we report the differential role of PTEN in chemotactic guidance of axonal growth cone...
Autores principales: | Henle, Steven J., Carlstrom, Lucas P., Cheever, Thomas R., Henley, John R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774355/ https://www.ncbi.nlm.nih.gov/pubmed/23775074 http://dx.doi.org/10.1074/jbc.C113.487066 |
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