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Characterization of the Human Sigma-1 Receptor Chaperone Domain Structure and Binding Immunoglobulin Protein (BiP) Interactions

The sigma-1 receptor (S1R) is a ligand-regulated membrane protein chaperone involved in the ER stress response. S1R activity is implicated in diseases of the central nervous system including amnesia, schizophrenia, depression, Alzheimer disease, and addiction. S1R has been shown previously to regula...

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Detalles Bibliográficos
Autores principales:	Ortega-Roldan, Jose Luis, Ossa, Felipe, Schnell, Jason R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2013
Materias:	Protein Structure and Folding
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774411/ https://www.ncbi.nlm.nih.gov/pubmed/23760505 http://dx.doi.org/10.1074/jbc.M113.450379

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