BMP7 Activates Brown Adipose Tissue and Reduces Diet-Induced Obesity Only at Subthermoneutrality

BACKGROUND/AIMS: Brown adipose tissue (BAT) dissipates energy stored in triglycerides as heat via the uncoupling protein UCP-1 and is a promising target to combat hyperlipidemia and obesity. BAT is densely innervated by the sympathetic nervous system, which increases BAT differentiation and activity...

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Detalles Bibliográficos
Autores principales: Boon, Mariëtte R., van den Berg, Sjoerd A. A., Wang, Yanan, van den Bossche, Jan, Karkampouna, Sofia, Bauwens, Matthias, De Saint-Hubert, Marijke, van der Horst, Geertje, Vukicevic, Slobodan, de Winther, Menno P. J., Havekes, Louis M., Jukema, J. Wouter, Tamsma, Jouke T., van der Pluijm, Gabri, van Dijk, Ko Willems, Rensen, Patrick C. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774620/
https://www.ncbi.nlm.nih.gov/pubmed/24066098
http://dx.doi.org/10.1371/journal.pone.0074083

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