Performance Comparison of Bench-Top Next Generation Sequencers Using Microdroplet PCR-Based Enrichment for Targeted Sequencing in Patients with Autism Spectrum Disorder

Next-generation sequencing (NGS) combined with enrichment of target genes enables highly efficient and low-cost sequencing of multiple genes for genetic diseases. The aim of this study was to validate the accuracy and sensitivity of our method for comprehensive mutation detection in autism spectrum...

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Detalles Bibliográficos
Autores principales: Koshimizu, Eriko, Miyatake, Satoko, Okamoto, Nobuhiko, Nakashima, Mitsuko, Tsurusaki, Yoshinori, Miyake, Noriko, Saitsu, Hirotomo, Matsumoto, Naomichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774667/
https://www.ncbi.nlm.nih.gov/pubmed/24066114
http://dx.doi.org/10.1371/journal.pone.0074167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774667/
https://www.ncbi.nlm.nih.gov/pubmed/24066114
http://dx.doi.org/10.1371/journal.pone.0074167

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