Cargando…

Genetic Substructure of Kuwaiti Population Reveals Migration History

The State of Kuwait is characterized by settlers from Saudi Arabia, Iran, and other regions of the Arabian Peninsula. The settlements and subsequent admixtures have shaped the genetics of Kuwait. High prevalence of recessive disorders and metabolic syndromes (that increase risk of diabetes) is seen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alsmadi, Osama, Thareja, Gaurav, Alkayal, Fadi, Rajagopalan, Ramakrishnan, John, Sumi Elsa, Hebbar, Prashantha, Behbehani, Kazem, Thanaraj, Thangavel Alphonse
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774671/ https://www.ncbi.nlm.nih.gov/pubmed/24066156 http://dx.doi.org/10.1371/journal.pone.0074913

Ejemplares similares

Kuwaiti population subgroup of nomadic Bedouin ancestry—Whole genome sequence and analysis
por: John, Sumi Elsa, et al.
Publicado: (2014)

Sequence and analysis of a whole genome from Kuwaiti population subgroup of Persian ancestry
por: Thareja, Gaurav, et al.
Publicado: (2015)

Genome at Juncture of Early Human Migration: A Systematic Analysis of Two Whole Genomes and Thirteen Exomes from Kuwaiti Population Subgroup of Inferred Saudi Arabian Tribe Ancestry
por: Alsmadi, Osama, et al.
Publicado: (2014)

Genetic risk variants for metabolic traits in Arab populations
por: Hebbar, Prashantha, et al.
Publicado: (2017)

Assessment of coding region variants in Kuwaiti population: implications for medical genetics and population genomics
por: John, Sumi Elsa, et al.
Publicado: (2018)

MC4R Variant rs17782313 Associates With Increased Levels of DNAJC27, Ghrelin, and Visfatin and Correlates With Obesity and Hypertension in a Kuwaiti Cohort
por: Hammad, Maha M., et al.
Publicado: (2020)

Linkage analysis using whole exome sequencing data implicates SLC17A1, SLC17A3, TATDN2 and TMEM131L in type 1 diabetes in Kuwaiti families
por: Hebbar, Prashantha, et al.
Publicado: (2023)

Genome-wide landscape establishes novel association signals for metabolic traits in the Arab population
por: Hebbar, Prashantha, et al.
Publicado: (2020)

Genome-wide association study identifies novel risk variants from RPS6KA1, CADPS, VARS, and DHX58 for fasting plasma glucose in Arab population
por: Hebbar, Prashantha, et al.
Publicado: (2020)

FTO Variant rs1421085 Associates With Increased Body Weight, Soft Lean Mass, and Total Body Water Through Interaction With Ghrelin and Apolipoproteins in Arab Population
por: Hebbar, Prashantha, et al.
Publicado: (2020)

PharmaKU: A Web-Based Tool Aimed at Improving Outreach and Clinical Utility of Pharmacogenomics
por: John, Sumi Elsa, et al.
Publicado: (2021)

Sudden cardiac death diagnosed with dilated cardiomyopathy in a Kuwaiti family: a case report
por: Bulbanat, Bassam, et al.
Publicado: (2014)

Unraveling a fine-scale high genetic heterogeneity and recent continental connections of an Arabian Peninsula population
por: Eaaswarkhanth, Muthukrishnan, et al.
Publicado: (2021)

ANGPTL3 Variants Associate with Lower Levels of Irisin and C-Peptide in a Cohort of Arab Individuals
por: Alanbaei, Muath, et al.
Publicado: (2021)

Differentially methylated and expressed genes in familial type 1 diabetes
por: Dashti, Mohammed, et al.
Publicado: (2022)

Impact of Hypertension on the Association of BMI with Risk and Age at Onset of Type 2 Diabetes Mellitus: Age- and Gender-Mediated Modifications
por: Channanath, Arshad Mohamed, et al.
Publicado: (2014)

Predictive models to assess risk of type 2 diabetes, hypertension and comorbidity: machine-learning algorithms and validation using national health data from Kuwait—a cohort study
por: Farran, Bassam, et al.
Publicado: (2013)

State of Diabetes, Hypertension, and Comorbidity in Kuwait: Showcasing the Trends as Seen in Native Versus Expatriate Populations
por: Channanath, Arshad Mohamed, et al.
Publicado: (2013)

Association between body mass index and onset of hypertension in men and women with and without diabetes: a cross-sectional study using national health data from the State of Kuwait in the Arabian Peninsula
por: Channanath, Arshad Mohamed, et al.
Publicado: (2015)

Delineation of Mitochondrial DNA Variants From Exome Sequencing Data and Association of Haplogroups With Obesity in Kuwait
por: Dashti, Mohammed, et al.
Publicado: (2021)

Distribution of HLA-B Alleles and Haplotypes in Qatari: Recommendation for Establishing Pharmacogenomic Markers Screening for Drug Hypersensitivity
por: Dashti, Mohammed, et al.
Publicado: (2022)

A Perception on Genome-Wide Genetic Analysis of Metabolic Traits in Arab Populations
por: Hebbar, Prashantha, et al.
Publicado: (2019)

Generalizability of GWA-Identified Genetic Risk Variants for Metabolic Traits to Populations from the Arabian Peninsula
por: Hebbar, Prashantha, et al.
Publicado: (2021)

Relevance between COVID-19 and host genetics of immune response
por: Taher, Ibrahim, et al.
Publicado: (2021)

Association between alleles, haplotypes, and amino acid variations in HLA class II genes and type 1 diabetes in Kuwaiti children
por: Dashti, Mohammed, et al.
Publicado: (2023)

Unhealthy Phenotype as Indicated by Salivary Biomarkers: Glucose, Insulin, VEGF-A, and IL-12p70 in Obese Kuwaiti Adolescents
por: Hartman, Mor-Li, et al.
Publicado: (2016)

Vitamin D Insufficiency in Arabs and South Asians Positively Associates with Polymorphisms in GC and CYP2R1 Genes
por: Elkum, Naser, et al.
Publicado: (2014)

Caveolin-1 rs1997623 variant and adult metabolic syndrome—Assessing the association in three ethnic cohorts of Arabs, South Asians and South East Asians
por: Al Madhoun, Ashraf, et al.
Publicado: (2022)

The Proinflammatory Role of ANGPTL8 R59W Variant in Modulating Inflammation through NF-κB Signaling Pathway under TNFα Stimulation
por: Abu-Farha, Mohamed, et al.
Publicado: (2023)

A Review of Adult Obesity Prevalence, Trends, Risk Factors, and Epidemiologic Methods in Kuwait
por: Karageorgi, Stalo, et al.
Publicado: (2013)

Specific and complete human genome amplification with improved yield achieved by phi29 DNA polymerase and a novel primer at elevated temperature
por: Alsmadi, Osama, et al.
Publicado: (2009)

SARS-CoV-2: Possible recombination and emergence of potentially more virulent strains
por: Haddad, Dania, et al.
Publicado: (2021)

ND4L gene concurrent 10609T>C and 10663T>C mutations are associated with Leber's hereditary optic neuropathy in a large pedigree from Kuwait
por: Behbehani, Raed, et al.
Publicado: (2014)

Prognostic Genetic Markers for Thrombosis in COVID-19 Patients: A Focused Analysis on D-Dimer, Homocysteine and Thromboembolism
por: Abu-Farha, Mohamed, et al.
Publicado: (2020)

The miR-668 binding site variant rs1046322 on WFS1 is associated with obesity in Southeast Asians
por: Hammad, Maha M., et al.
Publicado: (2023)

GALNT2 rs4846914 SNP Is Associated with Obesity, Atherogenic Lipid Traits, and ANGPTL3 Plasma Level
por: Qaddoumi, Mohammad, et al.
Publicado: (2022)

Insight into the impact of diabetes mellitus on the increased risk of hepatocellular carcinoma: mini-review
por: Ali Kamkar, Maisa Mahmoud, et al.
Publicado: (2014)

ONECUT1 variants beyond type 1 and type 2 diabetes: exploring clinical diversity and epigenetic associations in Arab cohorts
por: Dashti, Mohammed, et al.
Publicado: (2023)

Salivary N1-Methyl-2-Pyridone-5-Carboxamide, a Biomarker for Uranium Uptake, in Kuwaiti Children Exhibiting Exceptional Weight Gain
por: Goodson, Jo Max, et al.
Publicado: (2019)

Bacterial and fungal communities in indoor aerosols from two Kuwaiti hospitals
por: Habibi, Nazima, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_rp1chfi6i04bi22740kjic78kc