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Sinomenine Suppresses Osteoclast Formation and Mycobacterium tuberculosis H37Ra-Induced Bone Loss by Modulating RANKL Signaling Pathways

Receptor activator of NF-κB ligand (RANKL) is essential for osteoclastogenesis. Targeting RANKL signaling pathways has been an encouraging strategy for treating lytic bone diseases such as osteoporosis and rheumatoid arthritis (RA). Sinomenine (SIN), derived from Chinese medicinal plant Sinomenioum...

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Detalles Bibliográficos
Autores principales:	Li, Xiaojuan, He, Longgang, Hu, Yiping, Duan, Heng, Li, Xianglian, Tan, Suiyi, Zou, Min, Gu, Chunping, Zeng, Xiangzhou, Yu, Le, Xu, Jiake, Liu, Shuwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774760/ https://www.ncbi.nlm.nih.gov/pubmed/24066131 http://dx.doi.org/10.1371/journal.pone.0074274

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