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Deficiency in Repair of the Mitochondrial Genome Sensitizes Proliferating Myoblasts to Oxidative Damage

Reactive oxygen species (ROS), generated as a by-product of mitochondrial oxidative phosphorylation, are particularly damaging to the genome of skeletal muscle because of their high oxygen consumption. Proliferating myoblasts play a key role during muscle regeneration by undergoing myogenic differen...

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Detalles Bibliográficos
Autores principales:	Szczesny, Bartosz, Olah, Gabor, Walker, Dillon K., Volpi, Elena, Rasmussen, Blake B., Szabo, Csaba, Mitra, Sankar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774773/ https://www.ncbi.nlm.nih.gov/pubmed/24066171 http://dx.doi.org/10.1371/journal.pone.0075201

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