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Physical Motif Clustering within Intrinsically Disordered Nucleoporin Sequences Reveals Universal Functional Features
Bioinformatics of disordered proteins is especially challenging given high mutation rates for homologous proteins and that functionality may not be strongly related to sequence. Here we have performed a novel bioinformatic analysis, based on the spatial clustering of physically relevant features suc...
Autores principales: | Ando, David, Colvin, Michael, Rexach, Michael, Gopinathan, Ajay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774778/ https://www.ncbi.nlm.nih.gov/pubmed/24066078 http://dx.doi.org/10.1371/journal.pone.0073831 |
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