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Patterns of Rotavirus Vaccine Uptake and Use in Privately-Insured US Infants, 2006–2010

Rotavirus vaccines are highly effective at preventing gastroenteritis in young children and are now universally recommended for infants in the US. We studied patterns of use of rotavirus vaccines among US infants with commercial insurance. We identified a large cohort of infants in the MarketScan Re...

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Autores principales: Panozzo, Catherine A., Becker-Dreps, Sylvia, Pate, Virginia, Jonsson Funk, Michele, Stürmer, Til, Weber, David J., Brookhart, M. Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774785/
https://www.ncbi.nlm.nih.gov/pubmed/24066076
http://dx.doi.org/10.1371/journal.pone.0073825
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author Panozzo, Catherine A.
Becker-Dreps, Sylvia
Pate, Virginia
Jonsson Funk, Michele
Stürmer, Til
Weber, David J.
Brookhart, M. Alan
author_facet Panozzo, Catherine A.
Becker-Dreps, Sylvia
Pate, Virginia
Jonsson Funk, Michele
Stürmer, Til
Weber, David J.
Brookhart, M. Alan
author_sort Panozzo, Catherine A.
collection PubMed
description Rotavirus vaccines are highly effective at preventing gastroenteritis in young children and are now universally recommended for infants in the US. We studied patterns of use of rotavirus vaccines among US infants with commercial insurance. We identified a large cohort of infants in the MarketScan Research Databases, 2006–2010. The analysis was restricted to infants residing in states without state-funded rotavirus vaccination programs. We computed summary statistics and used multivariable regression to assess the association between patient-, provider-, and ecologic-level variables of rotavirus vaccine receipt and series completion. Approximately 69% of 594,117 eligible infants received at least one dose of rotavirus vaccine from 2006–2010. Most infants received the rotavirus vaccines at the recommended ages, but more infants completed the series for monovalent rotavirus vaccine than pentavalent rotavirus vaccine or a mix of the vaccines (87% versus 79% versus 73%, P<0.001). In multivariable analyses, the strongest predictors of rotavirus vaccine series initiation and completion were receipt of the diphtheria, tetanus and acellular pertussis vaccine (Initiation: RR = 7.91, 95% CI = 7.69–8.13; Completion: RR = 1.26, 95% CI = 1.23–1.29), visiting a pediatrician versus family physician (Initiation: RR = 1.51, 95% CI = 1.49–1.52; Completion: RR = 1.13, 95% CI = 1.11–1.14), and living in a large metropolitan versus smaller metropolitan, urban, or rural area. We observed rapid diffusion of the rotavirus vaccine in routine practice; however, approximately one-fifth of infants did not receive at least one dose of vaccine as recently as 2010. Interventions to increase rotavirus vaccine coverage should consider targeting family physicians and encouraging completion of the vaccine series.
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spelling pubmed-37747852013-09-24 Patterns of Rotavirus Vaccine Uptake and Use in Privately-Insured US Infants, 2006–2010 Panozzo, Catherine A. Becker-Dreps, Sylvia Pate, Virginia Jonsson Funk, Michele Stürmer, Til Weber, David J. Brookhart, M. Alan PLoS One Research Article Rotavirus vaccines are highly effective at preventing gastroenteritis in young children and are now universally recommended for infants in the US. We studied patterns of use of rotavirus vaccines among US infants with commercial insurance. We identified a large cohort of infants in the MarketScan Research Databases, 2006–2010. The analysis was restricted to infants residing in states without state-funded rotavirus vaccination programs. We computed summary statistics and used multivariable regression to assess the association between patient-, provider-, and ecologic-level variables of rotavirus vaccine receipt and series completion. Approximately 69% of 594,117 eligible infants received at least one dose of rotavirus vaccine from 2006–2010. Most infants received the rotavirus vaccines at the recommended ages, but more infants completed the series for monovalent rotavirus vaccine than pentavalent rotavirus vaccine or a mix of the vaccines (87% versus 79% versus 73%, P<0.001). In multivariable analyses, the strongest predictors of rotavirus vaccine series initiation and completion were receipt of the diphtheria, tetanus and acellular pertussis vaccine (Initiation: RR = 7.91, 95% CI = 7.69–8.13; Completion: RR = 1.26, 95% CI = 1.23–1.29), visiting a pediatrician versus family physician (Initiation: RR = 1.51, 95% CI = 1.49–1.52; Completion: RR = 1.13, 95% CI = 1.11–1.14), and living in a large metropolitan versus smaller metropolitan, urban, or rural area. We observed rapid diffusion of the rotavirus vaccine in routine practice; however, approximately one-fifth of infants did not receive at least one dose of vaccine as recently as 2010. Interventions to increase rotavirus vaccine coverage should consider targeting family physicians and encouraging completion of the vaccine series. Public Library of Science 2013-09-16 /pmc/articles/PMC3774785/ /pubmed/24066076 http://dx.doi.org/10.1371/journal.pone.0073825 Text en © 2013 Panozzo et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Panozzo, Catherine A.
Becker-Dreps, Sylvia
Pate, Virginia
Jonsson Funk, Michele
Stürmer, Til
Weber, David J.
Brookhart, M. Alan
Patterns of Rotavirus Vaccine Uptake and Use in Privately-Insured US Infants, 2006–2010
title Patterns of Rotavirus Vaccine Uptake and Use in Privately-Insured US Infants, 2006–2010
title_full Patterns of Rotavirus Vaccine Uptake and Use in Privately-Insured US Infants, 2006–2010
title_fullStr Patterns of Rotavirus Vaccine Uptake and Use in Privately-Insured US Infants, 2006–2010
title_full_unstemmed Patterns of Rotavirus Vaccine Uptake and Use in Privately-Insured US Infants, 2006–2010
title_short Patterns of Rotavirus Vaccine Uptake and Use in Privately-Insured US Infants, 2006–2010
title_sort patterns of rotavirus vaccine uptake and use in privately-insured us infants, 2006–2010
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774785/
https://www.ncbi.nlm.nih.gov/pubmed/24066076
http://dx.doi.org/10.1371/journal.pone.0073825
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