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Metabolic Syndrome in Drug-naïve Patients with Depressive Disorders
BACKGROUND: The prevalence of metabolic syndrome (MS) is found to be higher in patients with depression than in the general population. As there is lack of data from India, this study aimed to assess the prevalence of MS in patients with depression who had never been treated with antidepressants for...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775049/ https://www.ncbi.nlm.nih.gov/pubmed/24049228 http://dx.doi.org/10.4103/0253-7176.116247 |
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author | Grover, Sandeep Nebhinani, Naresh Chakrabarti, Subho Avasthi, Ajit Kulhara, Parmanand |
author_facet | Grover, Sandeep Nebhinani, Naresh Chakrabarti, Subho Avasthi, Ajit Kulhara, Parmanand |
author_sort | Grover, Sandeep |
collection | PubMed |
description | BACKGROUND: The prevalence of metabolic syndrome (MS) is found to be higher in patients with depression than in the general population. As there is lack of data from India, this study aimed to assess the prevalence of MS in patients with depression who had never been treated with antidepressants for their depressive disorder and compare the same with a matched group of healthy controls. MATERIALS AND METHODS: Forty-three drug-naïve patients with depressive disorders and 43 age- and gender-matched healthy controls were assessed for the prevalence of MS as per the consensus definition. RESULTS: The prevalence of MS in patients with depression was 37.2% and was significantly higher than that seen in the healthy controls (16.3%). Increased waist circumference was the most common abnormality in both the study groups. Compared to healthy controls, a significantly higher proportion of patients with depression had abnormal waist circumference, systolic blood pressure, or high blood pressure. Besides 16 patients with depressive disorders having MS, another 53.5% of patients fulfilled one or two criteria of MS. None of the sociodemographic variables was associated with development of MS in patients with depression. CONCLUSIONS: Slightly more than one-third of depressed patients who are drug-naïve have MS and this prevalence rate is significantly higher than in healthy controls. |
format | Online Article Text |
id | pubmed-3775049 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-37750492013-09-18 Metabolic Syndrome in Drug-naïve Patients with Depressive Disorders Grover, Sandeep Nebhinani, Naresh Chakrabarti, Subho Avasthi, Ajit Kulhara, Parmanand Indian J Psychol Med Original Article BACKGROUND: The prevalence of metabolic syndrome (MS) is found to be higher in patients with depression than in the general population. As there is lack of data from India, this study aimed to assess the prevalence of MS in patients with depression who had never been treated with antidepressants for their depressive disorder and compare the same with a matched group of healthy controls. MATERIALS AND METHODS: Forty-three drug-naïve patients with depressive disorders and 43 age- and gender-matched healthy controls were assessed for the prevalence of MS as per the consensus definition. RESULTS: The prevalence of MS in patients with depression was 37.2% and was significantly higher than that seen in the healthy controls (16.3%). Increased waist circumference was the most common abnormality in both the study groups. Compared to healthy controls, a significantly higher proportion of patients with depression had abnormal waist circumference, systolic blood pressure, or high blood pressure. Besides 16 patients with depressive disorders having MS, another 53.5% of patients fulfilled one or two criteria of MS. None of the sociodemographic variables was associated with development of MS in patients with depression. CONCLUSIONS: Slightly more than one-third of depressed patients who are drug-naïve have MS and this prevalence rate is significantly higher than in healthy controls. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3775049/ /pubmed/24049228 http://dx.doi.org/10.4103/0253-7176.116247 Text en Copyright: © Indian Journal of Psychological Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Grover, Sandeep Nebhinani, Naresh Chakrabarti, Subho Avasthi, Ajit Kulhara, Parmanand Metabolic Syndrome in Drug-naïve Patients with Depressive Disorders |
title | Metabolic Syndrome in Drug-naïve Patients with Depressive Disorders |
title_full | Metabolic Syndrome in Drug-naïve Patients with Depressive Disorders |
title_fullStr | Metabolic Syndrome in Drug-naïve Patients with Depressive Disorders |
title_full_unstemmed | Metabolic Syndrome in Drug-naïve Patients with Depressive Disorders |
title_short | Metabolic Syndrome in Drug-naïve Patients with Depressive Disorders |
title_sort | metabolic syndrome in drug-naïve patients with depressive disorders |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775049/ https://www.ncbi.nlm.nih.gov/pubmed/24049228 http://dx.doi.org/10.4103/0253-7176.116247 |
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