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Protein breakdown in muscle wasting: Role of autophagy-lysosome and ubiquitin-proteasome()()
Skeletal muscle adapts its mass as consequence of physical activity, metabolism and hormones. Catabolic conditions or inactivity induce signaling pathways that regulate the process of muscle loss. Muscle atrophy in adult tissue occurs when protein degradation rates exceed protein synthesis. Two majo...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775123/ https://www.ncbi.nlm.nih.gov/pubmed/23665154 http://dx.doi.org/10.1016/j.biocel.2013.04.023 |